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NUP107 抗体 (C-Term)

This anti-NUP107 antibody is a 兔 多克隆 antibody detecting NUP107 in WB, ELISA, IF 和 ICC. Suitable for 人 和 大鼠.
产品编号 ABIN6990943
发货至: 中国

Quick Overview for NUP107 抗体 (C-Term) (ABIN6990943)

抗原

See all NUP107 抗体
NUP107 (Nucleoporin 107kDa (NUP107))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This NUP107 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 820-870, C-Term

    纯化方法

    NUP107 Antibody is affinity chromatography purified via peptide column.

    免疫原

    NUP107 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human NUP107. The immunogen is located within amino acids 820 - 870 of NUP107.

    亚型

    IgG
  • 应用备注

    NUP107 antibody can be used for detection of NUP107 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NUP107 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    NUP107 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    NUP107 (Nucleoporin 107kDa (NUP107))

    别名

    NUP107

    背景

    NUP107 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.

    基因ID

    57122

    UniProt

    P57740

    途径

    Protein targeting to Nucleus
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