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LASS5 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects LASS5 in WB, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6990940
发货至: 中国
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Quick Overview for LASS5 抗体 (C-Term) (ABIN6990940)

抗原

See all LASS5 抗体
LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

适用

  • 20
  • 19
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 34

克隆类型

  • 34
多克隆

标记

  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LASS5 antibody is un-conjugated

应用范围

  • 24
  • 13
  • 13
  • 9
  • 6
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    Multiple isoforms of LASS5 are known to exist. This antibody may cross-react with the highly homologous LASS6.

    纯化方法

    LASS5 Antibody is affinity chromatography purified via peptide column.

    免疫原

    LASS5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human LASS5. The immunogen is located within the last 50 amino acids of LASS5.

    亚型

    IgG
  • 应用备注

    LASS5 antibody can be used for detection of LASS5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunoflourescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    LASS5 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    LASS5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

    别名

    LASS5

    背景

    LASS5 Antibody: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis.

    基因ID

    91012

    NCBI登录号

    NP_671723

    UniProt

    Q8N5B7
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