Nanos Homolog 1 抗体 (N-Term)
Quick Overview for Nanos Homolog 1 抗体 (N-Term) (ABIN6990936)
抗原
See all Nanos Homolog 1 (NANOS1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
纯化方法
- Nanos1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- Nanos1 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Nanos1. The immunogen is located within the first 50 amino acids of Nanos1.
-
亚型
- IgG
-
-
anti-Nanos Homolog 1 (NANOS1) (AA 151-200) antibody
NANOS1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nanos Homolog 1 (NANOS1) (AA 50-100) antibodyNANOS1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nanos Homolog 1 (NANOS1) (AA 263-292), (C-Term) antibodyNANOS1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB13839 unconjugated
anti-Nanos Homolog 1 (NANOS1) (AA 206-270) antibodyNANOS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Nanos Homolog 1 (NANOS1) (C-Term) antibodyNANOS1 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Nanos Homolog 1 (NANOS1) (AA 1-292) antibodyNANOS1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nanos Homolog 1 (NANOS1) (AA 157-206) antibodyNANOS1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nanos Homolog 1 (NANOS1) (C-Term) antibodyVerified NANOS1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Nanos Homolog 1 (NANOS1) (AA 108-157) antibodyNANOS1 适用: 人, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Nanos Homolog 1 (NANOS1) antibodyNANOS1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Nanos1 antibody can be used for detection of Nanos1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Nanos1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- Nanos1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- Nanos Homolog 1 (NANOS1)
-
别名
- Nanos1
-
背景
- Nanos1 Antibody: Nanos1 is one of three known mammalian homologs to the Drosophila gene nanos. Nanos1 is an RNA-binding protein containing a zinc-finger motif and is expressed in the developing nervous system and continues in the adult brain. Interestingly, unlike mice deficient in either nanos2 or nanos3, mice lacking the nanos1 gene develop normally with no sign of abnormalities. Recently it has been found that expression of nanos1 mRNA is down-regulated by E-cadherin in a human breast cancer cell line and the amino-terminal domain on Nanos1 interacts with the E-cadherin-binding protein p120ctn. Furthermore, overexpression of Nanos1 in human colorectal DLD1 cancer cells functionally abolished cell-cell adhesion, allowing the cancer cells to develop strong migratory and invasive properties. These results suggest that targeting Nanos1 might prove an effective strategy in the treatment of E-cadherin-negative tumors.
-
基因ID
- 340719
-
UniProt
- Q8WY41
-
途径
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
抗原
-
