At least three isoforms of SAPAP2 are known to exist. This SAPAP2 antibody will not cross-react with other SAPAP proteins.
纯化方法
SAPAP2 Antibody is affinity chromatography purified via peptide column.
免疫原
SAPAP2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human SAPAP2. The immunogen is located within amino acids 480 - 530 of SAPAP2.
DLGAP2
适用: 人, 大鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
FITC
应用备注
SAPAP2 antibody can be used for detection of SAPAP2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
SAPAP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
SAPAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
DLGAP2
(Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
PSD-95 antibody, DAP2 antibody, SAPAP2 antibody, 6430596N04Rik antibody, Sapap2 antibody, DLG associated protein 2 antibody, disks large-associated protein 2 antibody, discs, large (Drosophila) homolog-associated protein 2a antibody, discs, large (Drosophila) homolog-associated protein 2 antibody, DLGAP2 antibody, LOC463960 antibody, dlgap2a antibody, LOC100447448 antibody, Dlgap2 antibody
背景
SAPAP2 Antibody: SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies.