GPAM 抗体 (C-Term)
Quick Overview for GPAM 抗体 (C-Term) (ABIN6990909)
抗原
See all GPAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 730-780, C-Term
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特异性
- At least four isoforms of GPAT1 are known to exist, this antibody will detect only the two largest isoforms.
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纯化方法
- GPAT1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- GPAT1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human GPAT1. The immunogen is located within amino acids 730 - 780 of GPAT1.
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亚型
- IgG
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anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 281-459) antibody
GPAM 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 611-710) antibodyGPAM 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 749-828) antibodyGPAM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 1-828) antibodyGPAM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 1-828) antibodyGPAM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 594-828) antibodyGPAM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 426-455) antibodyGPAM 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22518 unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (C-Term) antibodyGPAM 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) (AA 433-463), (Middle Region) antibodyGPAM 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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GPAT1 antibody can be used for detection of GPAT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GPAT1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GPAT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- GPAM (Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM))
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别名
- GPAT1
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背景
- GPAT1 Antibody: Glycerol-3-phosphate acyltransferase 1 (GPAT1), one of four known GPAT isoforms, is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis, steatosis triggered by GPAT1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets.
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分子量
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Predicted: 87, 91 kDa
Observed: 92 kDa -
基因ID
- 57678
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NCBI登录号
- NP_065969
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UniProt
- Q9HCL2
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途径
- Activated T Cell Proliferation
抗原
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