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RIMS2 抗体 (AA 250-300)

RIMS2 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990907
发货至: 中国
  • 抗原 See all RIMS2 抗体
    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
    抗原表位
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-300
    适用
    • 27
    • 14
    • 4
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 22
    • 10
    • 1
    克隆类型
    • 25
    • 8
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIMS2 antibody is un-conjugated
    应用范围
    • 14
    • 10
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    Multiple isoforms of RIM2 are known to exist. This antibody is predicted to have no cross-reactivity to other Rim proteins.
    纯化方法
    Rim2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Rim2 antibody was raised against a 17 amino acid synthetic peptide near the center of the human Rim2. The immunogen is located within amino acids 250 - 300 of Rim2.
    亚型
    IgG
    Top Product
    Discover our top product RIMS2 Primary Antibody
  • 应用备注
    Rim2 antibody can be used for detection of Rim2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rim2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Rim2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
    别名
    Rim2 (RIMS2 产品)
    别名
    OBOE antibody, RAB3IP3 antibody, RIM2 antibody, 2810036I15Rik antibody, AW048769 antibody, Rab3ip2 antibody, Rim2(+40A) antibody, Rim2(+44A) antibody, Rim2(+4A) antibody, Serg2 antibody, Syt3-rs antibody, mKIAA0751 antibody, Nim2 antibody, Rim2 antibody, RIMS2 antibody, MGC159469 antibody, rims2 antibody, zgc:73064 antibody, drs antibody, drsp antibody, mema antibody, np-a antibody, pinin antibody, pnn antibody, pnn-a antibody, pnn-b antibody, sdk3 antibody, regulating synaptic membrane exocytosis 2 antibody, regulating synaptic membrane exocytosis 2a antibody, pinin, desmosome associated protein S homeolog antibody, RIMS2 antibody, Rims2 antibody, rims2a antibody, pnn.S antibody
    背景
    Rim2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim 2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
    分子量
    Predicted: 39, 128, 148, 170 kDa

    Observed: 128 kDa
    基因ID
    9699
    NCBI登录号
    NP_001093587
    UniProt
    Q9UQ26
    途径
    Hormone Transport, Synaptic Vesicle Exocytosis
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