RIMS2 抗体 (AA 250-300)
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北京 101111
Quick Overview for RIMS2 抗体 (AA 250-300) (ABIN6990907)
抗原
See all RIMS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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特异性
- Multiple isoforms of RIM2 are known to exist. This antibody is predicted to have no cross-reactivity to other Rim proteins.
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纯化方法
- Rim2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rim2 antibody was raised against a 17 amino acid synthetic peptide near the center of the human Rim2. The immunogen is located within amino acids 250 - 300 of Rim2.
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亚型
- IgG
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anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 461-987) antibody
RIMS2 适用: 大鼠, 小鼠, 小鸡, Hamster, 斑马鱼 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (C-Term) antibodyRIMS2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 181-260) antibodyRIMS2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 909-1076) antibodyRIMS2 适用: 大鼠, 小鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 667-943) antibodyRIMS2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 181-260) antibodyRIMS2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 1-1163) antibodyRIMS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (AA 1-1163) antibodyRIMS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 2 (RIMS2) (Center) antibodyRIMS2 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Rim2 antibody can be used for detection of Rim2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rim2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Rim2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
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别名
- Rim2
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背景
- Rim2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim 2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
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分子量
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Predicted: 39, 128, 148, 170 kDa
Observed: 128 kDa -
基因ID
- 9699
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NCBI登录号
- NP_001093587
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UniProt
- Q9UQ26
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途径
- Hormone Transport, Synaptic Vesicle Exocytosis
抗原
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