COPS8 抗体 (C-Term)
Quick Overview for COPS8 抗体 (C-Term) (ABIN6990904)
抗原
See all COPS8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- CSN8 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- CSN8 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human CSN8. The immunogen is located within the last 50 amino acids of CSN8.
-
亚型
- IgG
-
-
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibody
COPS8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (Middle Region) antibodyCOPS8 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 150-198) antibodyCOPS8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (Internal Region) antibodyCOPS8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
CSN8 antibody can be used for detection of CSN8 by Western blot at 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- CSN8 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- CSN8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
-
别名
- CSN8
-
背景
- CSN8 Antibody: The COP9 signalosome (CSN) is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome. The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-comlpexes such as SCF, CSA or DDB2. It is also involved in phosphorylation of p53, c-jun/JUN, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN8 encodes the smallest and the least conserved but first identified subunit of CSN. Recent studies show CSN8 is essential for Drosophila development and is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.
-
基因ID
- 10920
-
NCBI登录号
- NP_006701
-
UniProt
- Q99627
-
途径
- Cell Division Cycle
抗原
-
