CADPS 抗体 (N-Term)
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Quick Overview for CADPS 抗体 (N-Term) (ABIN6990891)
抗原
See all CADPS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-140, N-Term
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特异性
- Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.
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纯化方法
- CAPS1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CAPS1 antibody was raised against a 21 amino acid synthetic peptide near the amino terminus of the human CAPS1. The immunogen is located within amino acids 90 - 140 of CAPS1.
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亚型
- IgG
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应用备注
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CAPS1 antibody can be used for detection of CAPS1 by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CAPS1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CAPS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CADPS (Ca++-Dependent Secretion Activator (CADPS))
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别名
- CAPS1
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背景
- CAPS1 Antibody: CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion.
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基因ID
- 8618
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NCBI登录号
- NP_899631
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UniProt
- Q9ULU8
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途径
- Synaptic Vesicle Exocytosis
抗原
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