AIFM3 抗体 (N-Term)
Quick Overview for AIFM3 抗体 (N-Term) (ABIN6990880)
抗原
See all AIFM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- AIFM3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- AIFM3 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human AIFM3. The immunogen is located within the first 50 amino acids of AIFM3.
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亚型
- IgG
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (AA 1-200) antibody
AIFM3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (AA 216-265) antibodyAIFM3 适用: 人, Cow, 豚鼠, 兔, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (AA 10-59) antibodyAIFM3 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (N-Term) antibodyAIFM3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3) (Middle Region) antibodyAIFM3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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AIFM3 antibody can be used for the detection of AIFM3 by Western blot at 0.5 and 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- AIFM3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- AIFM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
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别名
- AIFM3
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背景
- AIFM3 Antibody: Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.
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基因ID
- 150209
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UniProt
- Q96NN9
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途径
- Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
抗原
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