NIPSNAP (AA 130-180) 抗体
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北京 101111
Quick Overview for NIPSNAP (AA 130-180) 抗体 (ABIN6990879)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-180
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纯化方法
- NIPSNAP Antibody is affinity chromatography purified via peptide column.
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免疫原
- NIPSNAP antibody was raised against a 19 amino acid synthetic peptide from near the center of human NIPSNAP. The immunogen is located within amino acids 130 - 180 of NIPSNAP.
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亚型
- IgG
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应用备注
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NIPSNAP antibody can be used for the detection of NIPSNAP by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NIPSNAP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NIPSNAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NIPSNAP
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背景
- NIPSNAP Antibody: NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
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基因ID
- 8508
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NCBI登录号
- NP_003625
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UniProt
- Q9BPW8
抗原
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