LGI4 抗体 (AA 240-290)
This anti-LGI4 antibody is a 兔 多克隆 antibody detecting LGI4 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for LGI4 抗体 (AA 240-290) (ABIN6990873)
抗原
See all LGI4 抗体
LGI4
(Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This LGI4 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- AA 240-290
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特异性
- Two isoforms of LGI4 are known to exist, this LGI4 antibody will recognize only the larger form. This LGI4 antibody is predicted to be specific to LGI4 and not recognize other LGI proteins.
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纯化方法
- LGI4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- LGI4 antibody was raised against a 14 amino acid synthetic peptide from near the center of human LGI4. The immunogen is located within amino acids 240 - 290 of LGI4.
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亚型
- IgG
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anti-Leucine-Rich Repeat LGI Family, Member 4 (LGI4) (AA 292-412) antibody
LGI4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat LGI Family, Member 4 (LGI4) (Internal Region) antibodyLGI4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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LGI4 antibody can be used for the detection of LGI4 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LGI4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LGI4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
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别名
- LGI4
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背景
- LGI4 Antibody: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with ADTLE. However, the LGI4 gene is located in a region linked to benign familial infantile convulsions. Further study revealed that a GC-to-AT polymorphism was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.
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基因ID
- 163175
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UniProt
- Q8N135
抗原
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