LGI2 抗体 (N-Term)
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北京 101111
Quick Overview for LGI2 抗体 (N-Term) (ABIN6990865)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This LGI2 antibody is predicted to be specific to LGI2 and not recognize other LGI proteins. Three isoforms of LGI2 are known to exist, this LGI2 antibody will recognize only the longest.
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纯化方法
- LGI2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- LGI2 antibody was raised against a 11 amino acid synthetic peptide from near the amino terminus of human LGI2. The immunogen is located within the first 50 amino acids of LGI2.
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亚型
- IgG
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应用备注
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LGI2 antibody can be used for the detection of LGI2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LGI2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LGI2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))
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别名
- LGI2
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背景
- LGI2 Antibody: The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
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基因ID
- 246316
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UniProt
- Q8K4Z0, Q8N0V4
抗原
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