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LGI1 抗体 (AA 370-420)

This anti-LGI1 antibody is a 兔 多克隆 antibody detecting LGI1 in WB, ELISA, IF 和 IHC (p). Suitable for 小鼠, 人 和 大鼠.
产品编号 ABIN6990864
发货至: 中国

Quick Overview for LGI1 抗体 (AA 370-420) (ABIN6990864)

抗原

See all LGI1 抗体
LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

适用

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小鼠, 人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This LGI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 17
    • 15
    • 4
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 370-420

    特异性

    This LGI1 antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.

    纯化方法

    LGI1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    LGI1 antibody was raised against a 14 amino acid synthetic peptide from near the center of human LGI1. The immunogen is located within amino acids 370 - 420 of LGI1.

    亚型

    IgG
  • 应用备注

    LGI1 antibody can be used for the detection of LGI1 by Western blot at 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    LGI1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    LGI1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

    别名

    LGI1

    背景

    LGI1 Antibody: The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, this LGI1 antibody will recognize only the longer form.

    基因ID

    9211

    UniProt

    O95970
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