SLITRK2 抗体 (AA 650-700)
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北京 101111
Quick Overview for SLITRK2 抗体 (AA 650-700) (ABIN6990852)
抗原
See all SLITRK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 650-700
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特异性
- This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
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纯化方法
- Slitrk2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Slitrk2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human Slitrk2. The immunogen is located within amino acids 650 - 700 of Slitrk2.
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亚型
- IgG
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应用备注
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Slitrk2 antibody can be used for detection of Slitrk2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Slitrk2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Slitrk2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
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别名
- Slitrk2
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背景
- Slitrk2 Antibody: SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.
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基因ID
- 84631
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UniProt
- Q9H156
抗原
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