FBXL20 抗体 (C-Term)
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Quick Overview for FBXL20 抗体 (C-Term) (ABIN6990847)
抗原
See all FBXL20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- SCRAPPER Antibody is affinity chromatography purified via peptide column.
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免疫原
- SCRAPPER antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of the human SCRAPPER. The immunogen is located within the last 50 amino acids of SCRAPPER.
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亚型
- IgG
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anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 1-137) antibody
FBXL20 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 1-436) antibodyFBXL20 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 110-159) antibodyFBXL20 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 176-225) antibodyFBXL20 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (C-Term) antibodyFBXL20 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (N-Term) antibodyFBXL20 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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SCRAPPER antibody can be used for detection of SCRAPPER by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SCRAPPER Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SCRAPPER antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
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别名
- SCRAPPER
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背景
- SCRAPPER Antibody: Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.
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基因ID
- 84961
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NCBI登录号
- NP_116264
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UniProt
- Q96IG2
抗原
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