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RIMS2 抗体 (AA 840-890)

This anti-RIMS2 antibody is a 兔 多克隆 antibody detecting RIMS2 in ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN6990846
发货至: 中国

Quick Overview for RIMS2 抗体 (AA 840-890) (ABIN6990846)

抗原

See all RIMS2 抗体
RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

适用

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宿主

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克隆类型

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多克隆

标记

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This RIMS2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 840-890

    特异性

    RIM2 antibody is human specific. Multiple isoforms of RIM2 are known to exist.

    纯化方法

    RIM2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    RIM2 antibody was raised against a 17 amino acid synthetic peptide near the center of human RIM2. The immunogen is located within amino acids 840 - 890 of RIM2.

    亚型

    IgG
  • 应用备注

    RIM2 antibody can be used for detection of RIM2 by immunohistochemistry at 5 μ,g/mL.

    Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    RIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    RIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

    别名

    RIM2

    背景

    RIM2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.

    基因ID

    9699

    NCBI登录号

    NP_001093587

    UniProt

    Q9UQ26

    途径

    Hormone Transport, Synaptic Vesicle Exocytosis
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