Cathelicidin 抗体 (AA 50-100)
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Quick Overview for Cathelicidin 抗体 (AA 50-100) (ABIN6990841)
抗原
See all Cathelicidin (CAMP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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纯化方法
- Cathelicidin Antibody is affinity chromatography purified via peptide column.
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免疫原
- Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the center of the human Cathelicidin. The immunogen is located within amino acids 50 - 100 of Cathelicidin.
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亚型
- IgG
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应用备注
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Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Cathelicidin Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Cathelicidin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
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别名
- Cathelicidin
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背景
- Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
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分子量
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Predicted: 19 kDa
Observed: 18 kDa -
基因ID
- 820
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NCBI登录号
- NP_004336
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UniProt
- P49913
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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