SP110 抗体 (C-Term)
Quick Overview for SP110 抗体 (C-Term) (ABIN6990830)
抗原
See all SP110 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-520, C-Term
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纯化方法
- IPR1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- IPR1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human IPR1. The immunogen is located within amino acids 470 - 520 of IPR1.
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亚型
- IgG
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anti-SP110 Nuclear Body Protein (SP110) (AA 271-380) antibody
SP110 适用: 人 WB, ELISA, IHC (p), IP, RNAi 宿主: 小鼠 Monoclonal 8C8 unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 1-547) antibodySP110 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 271-380) antibodySP110 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6F11 unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 1-547) antibodySP110 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 271-380) antibodySP110 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (C-Term) antibodySP110 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 612-661) antibodySP110 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 1-290) antibodySP110 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (C-Term) antibodySP110 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Ipr1 antibody can be used for detection of Ipr1 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IPR1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IPR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SP110 (SP110 Nuclear Body Protein (SP110))
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别名
- IPR1
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背景
- IPR1 Antibody: Susceptibility to tuberculosis (TB) in mice has recently been attributed to the IPR1 gene. IPR1 is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. SP110 is the closest homolog of the IPR1 protein in humans. The IPR1/Sp110 gene product might play a role in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death, and pathogenesis. IPR1/Sp110 is up-regulated after infection with M. tuberculosis and required by Anaplasma phagocytophilum for infection of human promyelocytic cells. Defects in Sp110 are a cause of severely impaired resistance to infection by M. tuberculosis.
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基因ID
- 3431
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NCBI登录号
- NP_004501
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UniProt
- Q9HB58
抗原
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