GRIK5 抗体 (C-Term)
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Quick Overview for GRIK5 抗体 (C-Term) (ABIN6990825)
抗原
See all GRIK5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This Grik5 antibody does not cross-react with Grik4.
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纯化方法
- Grik5 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Grik5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Grik5. The immunogen is located within the last 50 amino acids of Grik5.
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亚型
- IgG
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应用备注
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Grik5 antibody can be used for detection of Grik5 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Grik5 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Grik5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))
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别名
- Grik5
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背景
- Grik5 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.
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基因ID
- 2901
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NCBI登录号
- NP_002079
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UniProt
- Q16478
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途径
- Carbohydrate Homeostasis, Synaptic Membrane, Maintenance of Protein Location, Synaptic Vesicle Exocytosis
抗原
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