GRIK1 抗体 (AA 380-430)
Quick Overview for GRIK1 抗体 (AA 380-430) (ABIN6990820)
抗原
See all GRIK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 380-430
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纯化方法
- Grik1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Grik1 antibody was raised against a 16 amino acid synthetic peptide near the center of the human Grik1. The immunogen is located within amino acids 380 - 430 of Grik1.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (AA 675-834) antibody
GRIK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (Internal Region) antibodyVerified GRIK1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (Extracellular) antibodyGRIK1 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (AA 331-440) antibodyGRIK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (AA 271-450) antibodyGRIK1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (AA 10-59) antibodyGRIK1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (Center) antibodyGRIK1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1) (C-Term) antibodyGRIK1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Grik1 antibody can be used for detection of Grik1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Grik1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Grik1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))
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别名
- Grik1
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背景
- Grik1 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.
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基因ID
- 2897
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UniProt
- P39086
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途径
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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