电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ARHGEF17 抗体 (AA 910-960)

This anti-ARHGEF17 antibody is a 兔 多克隆 antibody detecting ARHGEF17 in ELISA, WB 和 IHC (p). Suitable for 人.
产品编号 ABIN6990812
发货至: 中国

Quick Overview for ARHGEF17 抗体 (AA 910-960) (ABIN6990812)

抗原

See all ARHGEF17 抗体
ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

适用

  • 4
  • 2

宿主

  • 4

克隆类型

  • 4
多克隆

标记

  • 4
This ARHGEF17 antibody is un-conjugated

应用范围

  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    AA 910-960

    纯化方法

    TEM4 Antibody is affinity chromatography purified via peptide column.

    免疫原

    TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4. The immunogen is located within amino acids 910 - 960 of TEM4.

    亚型

    IgG
  • 应用备注

    TEM4 antibody can be used for detection of TEM4 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TEM4 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TEM4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

    别名

    TEM4

    背景

    TEM4 Antibody: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.

    分子量

    Predicted: 220 kDa

    Observed: 200 kDa

    基因ID

    9828

    UniProt

    Q96PE2
You are here:
Chat with us!