CD248 抗体 (N-Term)
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北京 101111
Quick Overview for CD248 抗体 (N-Term) (ABIN6990809)
抗原
See all CD248 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90, N-Term
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特异性
- At least two isoforms of TEM1 are known to exist, this antibody recognizes only the larger isoform.
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纯化方法
- TEM1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-TEM-1 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TEM-1. The immunogen is located within amino acids 40-90 of TEM-1
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亚型
- IgG
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anti-CD248 Molecule, Endosialin (CD248) (AA 251-350) antibody
CD248 适用: 人, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 18-180) antibodyCD248 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1H11A10 unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 18-150) antibodyCD248 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 18-757) antibodyCD248 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-CD248 Molecule, Endosialin (CD248) (C-Term) antibodyCD248 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (C-Term) antibodyCD248 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (C-Term) antibodyCD248 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 1-757) antibodyCD248 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 1-757) antibodyCD248 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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WB: 0.5-2 μ,g/mL, IHC-P: 2.5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TEM1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TEM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CD248 (CD248 Molecule, Endosialin (CD248))
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别名
- TEM1
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背景
- TEM1 Antibody: Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion.
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分子量
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Predicted: 81kD
Observed: 90 kD (post-modifications: 27 O-linked glycosylations) kDa -
基因ID
- 57124
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NCBI登录号
- NP_065137
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UniProt
- Q9HCU0
抗原
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