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TRIM25 抗体 (N-Term)

TRIM25 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990790
发货至: 中国
  • 抗原 See all TRIM25 抗体
    TRIM25 (Tripartite Motif Containing 25 (TRIM25))
    抗原表位
    • 15
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-90, N-Term
    适用
    • 82
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 76
    • 6
    克隆类型
    • 77
    • 5
    多克隆
    标记
    • 40
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TRIM25 antibody is un-conjugated
    应用范围
    • 77
    • 34
    • 27
    • 27
    • 13
    • 13
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    纯化方法
    TRIM25 Antibody is affinity chromatography purified via peptide column.
    免疫原
    TRIM25 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human TRIM25. The immunogen is located within amino acids 40 - 90 of TRIM25.
    亚型
    IgG
    Top Product
    Discover our top product TRIM25 Primary Antibody
  • 应用备注
    TRIM25 antibody can be used for detection of TRIM25 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TRIM25 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TRIM25 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TRIM25 (Tripartite Motif Containing 25 (TRIM25))
    别名
    TRIM25 (TRIM25 产品)
    别名
    zgc:55773 antibody, MGC130751 antibody, EFP antibody, RNF147 antibody, Z147 antibody, ZNF147 antibody, AA960166 antibody, AL022677 antibody, Zfp147 antibody, Efp antibody, Znf147 antibody, E3 ubiquitin/ISG15 ligase TRIM25 antibody, tripartite motif containing 25 antibody, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog antibody, microRNA 3614 antibody, tripartite motif-containing 25 antibody, LOC100146440 antibody, trim25 antibody, LOC100490741.L antibody, TRIM25 antibody, MIR3614 antibody, Trim25 antibody
    背景
    TRIM25 Antibody: TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family and is a downstream target of estrogen receptor a. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demonstrating that this protein is essential for estrogen dependent proliferation. TRIM25 expression is increased in breast carcinoma where it promotes the growth of breast tumor by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3s. Recent reports have indicated that TRIM25 E3 ubiquitin ligase is essential for the retinoic-acid-inducible gene 1 (RIG-1) signaling pathway to elicit host antiviral innate immunity.
    基因ID
    7706
    NCBI登录号
    NP_005073
    UniProt
    Q14258
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