STEAP1 抗体 (AA 130-180)
Quick Overview for STEAP1 抗体 (AA 130-180) (ABIN6990785)
抗原
See all STEAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-180
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特异性
- This STEAP1 antibody does not cross-react with other STEAP proteins.
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纯化方法
- STEAP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- STEAP1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human STEAP1. The immunogen is located within amino acids 130 - 180 of STEAP1.
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亚型
- IgG
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anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 1-339) antibody
STEAP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F6-1F3 unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 3-69) antibodySTEAP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 1-70) antibodySTEAP1 适用: 人 WB, ELISA, IHC, IHC (p), IF, ICC 宿主: 小鼠 Monoclonal J2D2 unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 1-70) antibodySTEAP1 适用: 人 WB, ELISA, IHC, IF 宿主: 小鼠 Monoclonal J2D2 unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (N-Term) antibodySTEAP1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 106-155) antibodySTEAP1 适用: 人, 大鼠, 小鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 251-339) antibodySTEAP1 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (N-Term) antibodySTEAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 1-339) antibodySTEAP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 1-339) antibodySTEAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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STEAP1 antibody can be used for detection of STEAP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL. better
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- STEAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- STEAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
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别名
- STEAP1
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背景
- STEAP1 Antibody: The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. The normal function of STEAP is still uncertain, unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity. However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers. Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-positive human tumor cells, suggesting that STEAP1 may a potential target for cancer immunotherapy. At least three isoforms of STEAP1 are known to exist.
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基因ID
- 26872
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UniProt
- Q9UHE8
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途径
- Transition Metal Ion Homeostasis
抗原
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