FYB 抗体 (N-Term)
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- 抗原 See all FYB 抗体
- FYB (FYN-Binding Protein (FYB))
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抗原表位
- AA 60-110, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FYB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 纯化方法
- ADAP Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ADAP antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human ADAP. The immunogen is located within amino acids 60 - 110 of ADAP.
- 亚型
- IgG
- Top Product
- Discover our top product FYB Primary Antibody
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anti-FYN-Binding Protein (FYB) antibody
FYB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 678-829) antibodyFYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (Internal Region) antibodyVerified FYB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 646-695) antibodyFYB 适用: 人, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 39-88) antibodyFYB 适用: 人, 小鼠, 马, Pig, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (N-Term) antibodyFYB 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ADAP antibody can be used for detection of ADAP by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ADAP Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ADAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- FYB (FYN-Binding Protein (FYB))
- 别名
- ADAP (FYB 产品)
- 别名
- fyb antibody, ADAP antibody, PRO0823 antibody, SLAP-130 antibody, B630013F22Rik antibody, FYB-120/130 antibody, Slap130 antibody, p120/130 antibody, p120/p130 antibody, RGD1563421 antibody, FYN-binding protein antibody, FYN binding protein 1 antibody, FYN binding protein antibody, fyb antibody, FYB1 antibody, Fyb antibody, Fyb1 antibody
- 背景
- ADAP Antibody: The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-κ,B family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.
- 基因ID
- 2533
- NCBI登录号
- NP_001456
- UniProt
- O15117
- 途径
- TCR Signaling, Protein targeting to Nucleus
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