FYB 抗体 (C-Term)
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Quick Overview for FYB 抗体 (C-Term) (ABIN6990772)
抗原
See all FYB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 640-690, C-Term
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纯化方法
- ADAP Antibody is affinity chromatography purified via peptide column.
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免疫原
- ADAP antibody was raised against a 20 amino acid synthetic peptide from near the carboxy terminus of human ADAP. The immunogen is located within amino acids 640 - 690 of ADAP.
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亚型
- IgG
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anti-FYN-Binding Protein (FYB) antibody
FYB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 678-829) antibodyFYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (Internal Region) antibodyVerified FYB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 39-88) antibodyFYB 适用: 人, 小鼠, 马, Pig, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 646-695) antibodyFYB 适用: 人, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (N-Term) antibodyFYB 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ADAP antibody can be used for detection of ADAP by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ADAP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ADAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FYB (FYN-Binding Protein (FYB))
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别名
- ADAP
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背景
- ADAP Antibody: The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-κ,B family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.
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基因ID
- 2533
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NCBI登录号
- NP_001456
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UniProt
- O15117
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途径
- TCR Signaling, Protein targeting to Nucleus
抗原
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