IER3 抗体 (AA 40-90)
Quick Overview for IER3 抗体 (AA 40-90) (ABIN6990760)
抗原
See all IER3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90
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纯化方法
- IEX-1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- IEX1 antibody was raised against a 24 amino acid synthetic peptide near the center of human IEX1. The immunogen is located within amino acids 40 - 90 of IEX-1.
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亚型
- IgG
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anti-Immediate Early Response 3 (IER3) (AA 45-73), (N-Term) antibody
IER3 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (C-Term) antibodyIER3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (AA 38-65), (N-Term) antibodyIER3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB20475 unconjugated
anti-Immediate Early Response 3 (IER3) (AA 85-156) antibodyIER3 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (AA 1-82) antibodyIER3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (Center) antibodyIER3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IEX1 antibody can be used for detection of IEX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IEX-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IEX-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IER3 (Immediate Early Response 3 (IER3))
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别名
- IEX-1
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背景
- IEX-1 Antibody: IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-α,. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-κ,B/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.
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分子量
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Predicted: 17 kDa
Observed: 17 kDa -
基因ID
- 8870
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UniProt
- P46695
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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