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CRLF2 抗体 (AA 140-190)

This anti-CRLF2 antibody is a 兔 多克隆 antibody detecting CRLF2 in WB, ELISA, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN6990749
发货至: 中国

Quick Overview for CRLF2 抗体 (AA 140-190) (ABIN6990749)

抗原

See all CRLF2 抗体
CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CRLF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    AA 140-190

    特异性

    At least two isoforms of TSLP-R are known to exist, this antibody will recognize both isoforms.

    纯化方法

    TSLP Receptor Antibody is affinity chromatography purified via peptide column.

    免疫原

    TSLP Receptor antibody was raised against a 19 amino acid synthetic peptide from near the center of human TSLP receptor. The immunogen is located within amino acids 140 - 190 of TSLP Receptor.

    亚型

    IgG
  • 应用备注

    TSLP-R antibody can be used for detection of TSLP-R by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TSLP Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TSLP Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

    别名

    TSLP Receptor

    背景

    TSLP Receptor Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells, co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.

    分子量

    Predicted: 28, 41 kDa

    Observed: 53 kDa

    基因ID

    57914

    NCBI登录号

    NP_071431

    UniProt

    Q8CII9
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