NRN1 抗体 (AA 70-120)
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北京 101111
Quick Overview for NRN1 抗体 (AA 70-120) (ABIN6990738)
抗原
See all NRN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-120
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纯化方法
- Neuritin Antibody is affinity chromatography purified via peptide column.
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免疫原
- Neuritin antibody was raised against a 20 amino acid synthetic peptide from near the center of human neuritin. The immunogen is located within amino acids 70 - 120 of Neuritin.
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亚型
- IgG
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anti-Neuritin 1 (NRN1) (AA 51-142) antibody
NRN1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuritin 1 (NRN1) (AA 28-142) antibodyNRN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuritin 1 (NRN1) (Center) antibodyNRN1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Neuritin 1 (NRN1) (AA 28-116) antibodyNRN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neuritin antibody can be used for detection of Neuritin by Western blot at 5 and 10 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Neuritin Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Neuritin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NRN1 (Neuritin 1 (NRN1))
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别名
- Neuritin
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背景
- Neuritin Antibody: As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.
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分子量
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Predicted: 16 kDa
Observed: 15 kDa -
基因ID
- 51299
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NCBI登录号
- NP_057672
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UniProt
- Q9NPD7
抗原
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