Reticulon 4 抗体 (N-Term)
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- 抗原 See all Reticulon 4 (RTN4) 抗体
- Reticulon 4 (RTN4)
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Reticulon 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- At least five isoforms of Nogo are known to exist, this antibody is specific for NogoA.
- 纯化方法
- NogoA Antibody is affinity chromatography purified via peptide column.
- 免疫原
- NogoA antibody was raised against a 23 amino acid synthetic peptide from near the amino terminus of human NogoA. The immunogen is located within the first 50 amino acids of NogoA.
- 亚型
- IgG
- Top Product
- Discover our top product RTN4 Primary Antibody
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anti-Reticulon 4 (RTN4) (AA 501-515) antibody
RTN4 适用: 人, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 14-30) antibodyRTN4 适用: 人, 小鼠, 大鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 251-357) antibodyRTN4 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 301-400) antibodyRTN4 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 28-58) antibodyRTN4 适用: 人 WB 宿主: 兔 Polyclonal RB54371 unconjugated
anti-Reticulon 4 (RTN4) (AA 81-130) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴, 马, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 254-303) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴, 马, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Middle Region) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 马, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Center) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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NogoA antibody can be used for detection of NogoA by Western blot at 0.5 - 1 μ,g/mL. Despite its predicted molecular weight, NogoA typically migrates at 180 kDa in an SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- NogoA Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- NogoA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- Reticulon 4 (RTN4)
- 别名
- NogoA (RTN4 产品)
- 背景
- NogoA Antibody: NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS, blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients.
- 基因ID
- 57142
- NCBI登录号
- NP_065393
- UniProt
- Q9NQC3
- 途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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