SAMHD1 抗体 (C-Term, pThr592)
Our Local Distributor
北京 101111
Quick Overview for SAMHD1 抗体 (C-Term, pThr592) (ABIN6990713)
抗原
See all SAMHD1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term, pThr592
-
特异性
- Phospho-SAMHD1 antibody will only detect the phosphorylated form of SAMHD1.
-
纯化方法
- SAMHD1 (phospho Thr592) antibody is affinity chromatography purified via peptide column.
-
免疫原
- Anti-SAMHD1 (phospho Thr592) antibody was raised against a phosphorylated peptide corresponding to 18 amino acids near the carboxy terminus of human Phospho-SAMHD1 surrounding T592.
-
亚型
- IgG
-
-
-
-
应用备注
-
WB: 0.05-1 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- SAMHD1 (phospho Thr592) antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- SAMHD1 (phospho Thr592) antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
-
别名
- SAMHD1
-
背景
- The SAM domain and HD domain 1 (SAMHD1) protein is upregulated in response to viral infection and is thought to play a role in innate immunity (1). SAMHD1 blocks the infection of HIV-1 and SIVdeltaVpx before reverse transcription in macrophages and dendritic cells (2), and this restriction is regulated by phosphorylation of SAMHD1 (3). Mutations in this gene have been associated with Aicardi-Goutieres syndrome (1).
-
分子量
-
Predicted: 72kD
Observed: 72 kD kDa -
基因ID
- 25939
-
NCBI登录号
- NP_056289
-
UniProt
- Q9Y3Z3
抗原
-