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SAMHD1 抗体 (C-Term, pThr592)

This anti-SAMHD1 antibody is a 兔 多克隆 antibody detecting SAMHD1 in WB, ELISA, IF 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN6990713
发货至: 中国

Quick Overview for SAMHD1 抗体 (C-Term, pThr592) (ABIN6990713)

抗原

See all SAMHD1 抗体
SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SAMHD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term, pThr592

    特异性

    Phospho-SAMHD1 antibody will only detect the phosphorylated form of SAMHD1.

    纯化方法

    SAMHD1 (phospho Thr592) antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-SAMHD1 (phospho Thr592) antibody was raised against a phosphorylated peptide corresponding to 18 amino acids near the carboxy terminus of human Phospho-SAMHD1 surrounding T592.

    亚型

    IgG
  • 应用备注

    WB: 0.05-1 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SAMHD1 (phospho Thr592) antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    SAMHD1 (phospho Thr592) antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

    别名

    SAMHD1

    背景

    The SAM domain and HD domain 1 (SAMHD1) protein is upregulated in response to viral infection and is thought to play a role in innate immunity (1). SAMHD1 blocks the infection of HIV-1 and SIVdeltaVpx before reverse transcription in macrophages and dendritic cells (2), and this restriction is regulated by phosphorylation of SAMHD1 (3). Mutations in this gene have been associated with Aicardi-Goutieres syndrome (1).

    分子量

    Predicted: 72kD

    Observed: 72 kD kDa

    基因ID

    25939

    NCBI登录号

    NP_056289

    UniProt

    Q9Y3Z3
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