LIPE 抗体 (C-Term)
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北京 101111
Quick Overview for LIPE 抗体 (C-Term) (ABIN6990685)
抗原
See all LIPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 920-970, C-Term
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特异性
- Multiple isoforms of Lipe are known to exist.
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纯化方法
- Lipe Antibody is affinity chromatography purified via peptide column.
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免疫原
- Lipe antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Lipe. The immunogen is located within amino acids 920 - 970 of Lipe.
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亚型
- IgG
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anti-Lipase, Hormone-Sensitive (LIPE) (pSer554), (pSer855) antibody
LIPE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (pSer552) antibodyLIPE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (pSer863) antibodyLIPE 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (AA 1-251) antibodyLIPE 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (AA 822-849), (C-Term) antibodyLIPE 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17399 unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (pSer552) antibodyLIPE 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (pSer855) antibodyLIPE 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (AA 900-1000) antibodyLIPE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (pSer552) antibodyLIPE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lipase, Hormone-Sensitive (LIPE) (pSer855) antibodyLIPE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Lipe antibody can be used for detection of Lipe by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Lipe Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Lipe antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LIPE (Lipase, Hormone-Sensitive (LIPE))
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别名
- Lipe
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背景
- Lipe Antibody: Although initially described as an adipocyte-specific triacylglycerol lipase, Lipe (also known as hormone-specific lipase or HSL) is expressed in multiple tissues and cell lines. It plays multiple roles in lipid metabolism, including hormone-stimulated lipolysis in adipose tissue and the hydrolysis of cholesterol esters. Lipe is expressed as a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesterol esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Recently, it was observed that the lack of Lipe in genetically obese leptin-null mice inhibited obesity and adipogenesis, suggesting that Lipe plays a major role in adipocyte proliferation.
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分子量
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Predicted: 85, 90, 110, 118 kDa
Observed: 90 kDa -
基因ID
- 3991
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UniProt
- Q05469
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途径
- AMPK Signaling, Monocarboxylic Acid Catabolic Process, Lipid Metabolism
抗原
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