BCL2A1 抗体 (N-Term)
Quick Overview for BCL2A1 抗体 (N-Term) (ABIN6990658)
抗原
See all BCL2A1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- At least two isoforms of Bfl-1 are known to exist, this antibody will detect both isoforms.
-
纯化方法
- Bfl-1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- Bfl-1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Bfl-1. The immunogen is located within the first 50 amino acids of Bfl-1.
-
亚型
- IgG
-
-
anti-BCL2-Related Protein A1 (BCL2A1) antibody
BCL2A1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 3E4 unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (AA 1-175) antibodyBCL2A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (Internal Region) antibodyBCL2A1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (AA 53-81) antibodyBCL2A1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB16877 unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (AA 30-65), (Ala1) antibodyBCL2A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1251 unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (AA 63-92), (Middle Region) antibodyBCL2A1 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (AA 31-130) antibodyBCL2A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (Internal Region) antibodyVerified BCL2A1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (C-Term) antibodyBCL2A1 适用: 人, 大鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Related Protein A1 (BCL2A1) (C-Term) antibodyBCL2A1 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Bfl-1 antibody can be used for the detection of Bfl-1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Bfl-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- Bfl-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
-
别名
- Bfl-1
-
背景
- Bfl-1 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by caspase activation. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such member is multi-domain antiapoptotic protein Bfl-1, which is overexpressed in stomach and other cancers. Bfl-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. It is upregulated in cisplatin-resistant human bladder tumors, suggesting that its expression may be important for cisplatin resistance and inhibition of apoptosis in cancer cells. At least two isoforms of Bfl-1 are known to exist.
-
分子量
-
Predicted: 18, 19 kDa
Observed: 22 kDa -
基因ID
- 597
-
NCBI登录号
- NP_004040
-
UniProt
- Q16548
抗原
-
