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BCL2A1 抗体 (C-Term)

BCL2A1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990657
发货至: 中国
  • 抗原 See all BCL2A1 抗体
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    抗原表位
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 43
    • 19
    • 12
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 40
    • 3
    • 1
    克隆类型
    • 34
    • 10
    多克隆
    标记
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This BCL2A1 antibody is un-conjugated
    应用范围
    • 24
    • 16
    • 10
    • 7
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    At least two isoforms of Bfl-1 are known to exist, this antibody will only detect the larger isoform.
    纯化方法
    Bfl-1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Bfl-1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Bfl-1. The immunogen is located within the last 50 amino acids of Bfl-1.
    亚型
    IgG
    Top Product
    Discover our top product BCL2A1 Primary Antibody
  • 应用备注
    Bfl-1 antibody can be used for the detection of Bfl-1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Bfl-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Bfl-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    别名
    Bfl-1 (BCL2A1 产品)
    别名
    ACC-1 antibody, ACC-2 antibody, BCL2L5 antibody, BFL1 antibody, GRS antibody, HBPA1 antibody, Bcl2a1d antibody, BCL2A1 antibody, BCL2 related protein A1 antibody, BCL2-related protein A1 antibody, BCL2A1 antibody, Bcl2a1 antibody
    背景
    Bfl-1 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by caspase activation. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such member is multi-domain antiapoptotic protein Bfl-1, which is overexpressed in stomach and other cancers. Bfl-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. It is upregulated in cisplatin-resistant human bladder tumors, suggesting that its expression may be important for cisplatin resistance and inhibition of apoptosis in cancer cells.
    分子量
    Predicted: 19 kDa

    Observed: 20 kDa
    基因ID
    597
    NCBI登录号
    NP_004040
    UniProt
    Q16548
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