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IL-27 抗体 (AA 80-130)

This anti-IL-27 antibody is a 兔 多克隆 antibody detecting IL-27 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6990634
发货至: 中国

Quick Overview for IL-27 抗体 (AA 80-130) (ABIN6990634)

抗原

See all IL-27 (IL27) 抗体
IL-27 (IL27) (Interleukin 27 (IL27))

适用

  • 39
  • 38
  • 10
  • 1
人, 小鼠

宿主

  • 44
  • 13
  • 5
  • 2

克隆类型

  • 48
  • 16
多克隆

标记

  • 45
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-27 antibody is un-conjugated

应用范围

  • 49
  • 30
  • 14
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-130

    纯化方法

    IL-27 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-IL-27 antibody was raised against a peptide corresponding to 14 amino acids near the center of human IL-27. The immunogen is located within amino acids 80 - 130 of IL-27.

    亚型

    IgG
  • 应用备注

    WB: 2-4 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-27 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-27 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    IL-27 (IL27) (Interleukin 27 (IL27))

    别名

    IL-27

    背景

    IL-27 Antibody: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.

    分子量

    Predicted: 28 kDa

    Observed: 28 kDa

    基因ID

    246778

    NCBI登录号

    NP_663634

    UniProt

    Q8NEV9
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