IL-27 抗体 (N-Term)
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北京 101111
Quick Overview for IL-27 抗体 (N-Term) (ABIN6990633)
抗原
See all IL-27 (IL27) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- IL-27 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-IL-27 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human IL-27. The immunogen is located within the first 50 amino acids of IL-27.
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亚型
- IgG
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anti-Interleukin 27 (IL27) (AA 177-243) antibody
IL27 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F12 unconjugated
anti-Interleukin 27 (IL27) (C-Term) antibodyIL27 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 (IL27) (AA 1-243) antibodyIL27 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 (IL27) (AA 1-243) antibodyIL27 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 27 (IL27) (N-Term) antibodyIL27 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 (IL27) (AA 57-87) antibodyIL27 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB3263 unconjugated
anti-Interleukin 27 (IL27) antibodyIL27 适用: 小鼠 WB, ELISA, FACS, MA 宿主: 大鼠 Monoclonal 3H12-F10 unconjugated
anti-Interleukin 27 (IL27) (AA 29-243) antibodyIL27 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 (IL27) (AA 31-46) antibodyIL27 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 (IL27) antibodyIL27 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal B-G49 unconjugated
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应用备注
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WB: 0.5 - 4 μ,g/mL, ICC: 10 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-27 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-27 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL-27 (IL27) (Interleukin 27 (IL27))
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别名
- IL-27
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背景
- IL-27 Antibody: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.
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分子量
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Predicted: 28 kDa
Observed: 28 kDa -
基因ID
- 246778
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NCBI登录号
- NP_663634
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UniProt
- Q8NEV9
抗原
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