IL23 抗体 (N-Term)
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- 抗原 See all IL23 抗体
- IL23 (Interleukin 23 (IL23))
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抗原表位
- AA 40-90, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL23 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- IL-23 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-IL-23 antibody was raised against a peptide corresponding to 17 amino acids near the amino terminus of human IL-23. The immunogen is located within amino acids 40 - 90 of IL-23.
- 亚型
- IgG
- Top Product
- Discover our top product IL23 Primary Antibody
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- 应用备注
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WB: 0.25-2 μ,g/mL, IF: 20 μ,g/mL, IHC: 2 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunofluorescence and Immunohistochemistry in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- IL-23 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- IL-23 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- IL23 (Interleukin 23 (IL23))
- 别名
- IL-23 (IL23 产品)
- 背景
- IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-α, from activated T cells, and can stimulate macrophages to produce TNF-α, and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
- 分子量
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Predicted: 21kD
Observed: 22 kD kDa - 基因ID
- 51561
- UniProt
- Q9NPF7
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