IL-31 抗体 (AA 60-110)
Quick Overview for IL-31 抗体 (AA 60-110) (ABIN6990613)
抗原
See all IL-31 (IL31) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-110
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纯化方法
- IL-31 Antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-31 antibody was raised against a 18 amino acid synthetic peptide from near the center of human IL-31. The immunogen is located within amino acids 60 - 110 of IL-31.
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亚型
- IgG
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anti-Interleukin 31 (IL31) (AA 21-70) antibody
IL31 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 31-130) antibodyIL31 适用: 人 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 21-120) antibodyIL31 适用: 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 28-154) antibodyIL31 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 13-40), (N-Term) antibodyIL31 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22575 unconjugated
anti-Interleukin 31 (IL31) (AA 19-49), (N-Term) antibodyIL31 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) antibodyIL31 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 55-183) antibodyIL31 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Interleukin 31 (IL31) (AA 24-164) antibodyIL31 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G9 unconjugated
anti-Interleukin 31 (IL31) antibodyIL31 适用: 人 ELISA 宿主: 小鼠 Monoclonal SB118b unconjugated
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应用备注
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IL-31 antibody can be used for the detection of IL-31 by Western blot at 2.5 - 10 μ,g/mL. Despite its predicted size, IL-31 runs at approximately 27 - 30 kDa in SDS-PAGE. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-31 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-31 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL-31 (IL31) (Interleukin 31 (IL31))
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别名
- IL-31
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背景
- IL-31 Antibody: Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.
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基因ID
- 386653
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UniProt
- Q6EBC2
抗原
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