IL-31 抗体 (N-Term)
Quick Overview for IL-31 抗体 (N-Term) (ABIN6990612)
抗原
See all IL-31 (IL31) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 30-80, N-Term
-
纯化方法
- IL-31 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- IL-31 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of mouse IL-31. The immunogen is located within amino acids 30 - 80 of IL-31.
-
亚型
- IgG
-
-
anti-Interleukin 31 (IL31) (AA 21-70) antibody
IL31 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 31-130) antibodyIL31 适用: 人 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 21-120) antibodyIL31 适用: 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 28-154) antibodyIL31 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 13-40), (N-Term) antibodyIL31 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22575 unconjugated
anti-Interleukin 31 (IL31) (AA 19-49), (N-Term) antibodyIL31 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) antibodyIL31 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 55-183) antibodyIL31 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Interleukin 31 (IL31) (AA 24-164) antibodyIL31 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G9 unconjugated
anti-Interleukin 31 (IL31) antibodyIL31 适用: 人 ELISA 宿主: 小鼠 Monoclonal SB118b unconjugated
-
-
应用备注
-
IL-31 antibody can be used for the detection of IL-31 by Western blot at 2.5 - 10 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- IL-31 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- IL-31 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- IL-31 (IL31) (Interleukin 31 (IL31))
-
别名
- IL-31
-
背景
- IL-31 Antibody: Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.
-
基因ID
- 76399
-
UniProt
- Q6EAL8
抗原
-
