TNFSF18 抗体
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北京 101111
Quick Overview for TNFSF18 抗体 (ABIN6990563)
抗原
See all TNFSF18 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- GITRL Antibody is affinity chromatography purified via peptide column.
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免疫原
- GITRL antibody was raised against purified recombinant human GITR ligand.
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亚型
- IgG
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 101-199) antibody
TNFSF18 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 1-177) antibodyTNFSF18 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 70-199) antibodyTNFSF18 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) antibodyTNFSF18 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 68-177) antibodyTNFSF18 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 适用: 人 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) antibodyTNFSF18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 68-177) antibodyTNFSF18 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 适用: 小鼠 ELISA, FACS 宿主: 兔 Chimeric YGL386 unconjugated Recombinant Antibody
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应用备注
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GITRL antibody can be used for the detection of GITRL by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.
Antibody validated: Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GITRL Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GITRL antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
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别名
- GITRL
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背景
- GITRL Antibody: The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-κ,B and various mitogen-activated protein kinases. The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions. Its ligand GITRL is expressed in endothelial and antigen-presenting cells and can activate NF-κ,B, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR. Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-κ,B activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2.
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基因ID
- 8995
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UniProt
- Q9UNG2
抗原
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