Cadherin 13 抗体 (N-Term)
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Quick Overview for Cadherin 13 抗体 (N-Term) (ABIN6990560)
抗原
See all Cadherin 13 (CDH13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-200, N-Term
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特异性
- At least two isoforms of T-cadherin are known to exist.
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纯化方法
- T-cadherin Antibody is affinity chromatography purified via peptide column.
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免疫原
- T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin. The immunogen is located within amino acids 150 - 200 of T-cadherin.
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亚型
- IgG
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应用备注
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T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for for immunohistochemistry starting at 5 μ,g/mL and immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- T-cadherin Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- T-cadherin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Cadherin 13 (CDH13)
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别名
- T-cadherin
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背景
- T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.
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分子量
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Predicted: 78, 84 kDa
Observed: 85 kDa -
基因ID
- 956
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NCBI登录号
- NP_001248
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UniProt
- O75355
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途径
- EGFR Signaling Pathway, Cell-Cell Junction Organization
抗原
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