IRF8 抗体 (C-Term)
Quick Overview for IRF8 抗体 (C-Term) (ABIN6990493)
抗原
See all IRF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- IRF8 Antibody is affinity chromatography purified via peptide column.
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免疫原
- IRF8 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IRF8. The immunogen is located within the last 50 amino acids of IRF8.
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亚型
- IgG
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anti-Interferon Regulatory Factor 8 (IRF8) (AA 128-426) antibody
IRF8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (N-Term) antibodyIRF8 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 1-327) antibodyIRF8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 122-218) antibodyIRF8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (C-Term) antibodyVerified IRF8 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 35-84) antibodyIRF8 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Pig, Bat, 小鸡, Hamster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 241-269) antibodyIRF8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 384-409) antibodyIRF8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 128-426) antibodyIRF8 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 137-426) antibodyIRF8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IRF8 antibody can be used for detection of IRF8 by Western blot at 1 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IRF8 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IRF8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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别名
- IRF8
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背景
- IRF8 Antibody: Interferons (IFN)s are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Unlike IRF3, IRF8 appears to act as a negative regulator of IFN-induced genes in most cases, but IRF8 mediates activation of NF-κ,B by the toll-like receptor 9 (TLR9) after stimulation by unmethylated CpG DNA in dendritic cells. Finally, it has been shown that IRF8 decreases bcl-2 expression and thus may play a role in chronic myelogenous leukemia.
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基因ID
- 3394
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UniProt
- Q02556
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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