DAD1 抗体 (C-Term)
Quick Overview for DAD1 抗体 (C-Term) (ABIN6990464)
抗原
See all DAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- DAD1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- DAD1 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human DAD1. The immunogen is located within the last 50 amino acids of DAD1.
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亚型
- IgG
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anti-Defender Against Cell Death 1 (DAD1) (AA 1-113) antibody
DAD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Defender Against Cell Death 1 (DAD1) (AA 1-113) antibodyDAD1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B4-C8 unconjugated
anti-Defender Against Cell Death 1 (DAD1) (AA 1-100) antibodyDAD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Defender Against Cell Death 1 (DAD1) antibodyDAD1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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DAD1 antibody can be used for detection of DAD1 by Western blot at 0.5 to 2 μ,g/mL. Despite its predicted molecular weight, DAD1 migrates at ~22 kDa in SDS-PAGE. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DAD1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DAD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DAD1 (Defender Against Cell Death 1 (DAD1))
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别名
- DAD1
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背景
- DAD1 Antibody: Defender of cell death 1 (DAD1) was initially discovered in BHK21 cells as a negative regulator of programmed cell death, a process important for normal organism development and tissue homeostasis. DAD1 was later shown to be a subunit of the mammalian oligosaccharyltransferase complex and is required for its function and structural integrity. Mice lacking DAD1 express abnormal N-linked glycoproteins and undergo increased apoptotic-associated embryonic death. Furthermore, overexpression of DAD1 mRNA is seen in some human hepatocellular carcinomas, indicating it may also play a role in carcinogenesis. It should be noted that DAD1 is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.
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基因ID
- 1603
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UniProt
- P61803
抗原
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