BIRC6 抗体 (C-Term)
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北京 101111
Quick Overview for BIRC6 抗体 (C-Term) (ABIN6990463)
抗原
See all BIRC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4760-4810, C-Term
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特异性
- BRUCE antibody is human specific. Multiple isoforms of BRUCE are known to exist.
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纯化方法
- BRUCE Antibody is affinity chromatography purified via peptide column.
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免疫原
- BRUCE antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human BRUCE. The immunogen is located within amino acids 4760 - 4810 of BRUCE.
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亚型
- IgG
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anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) antibody
BIRC6 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) (AA 4810-4844) antibodyBIRC6 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56699 unconjugated
anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) (AA 4701-4857) antibodyBIRC6 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) (C-Term) antibodyVerified BIRC6 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) (AA 4576-4857) antibodyBIRC6 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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BRUCE antibody can be used for detection of BRUCE by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BRUCE Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BRUCE antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
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别名
- BRUCE
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背景
- BRUCE Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.
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分子量
- 534 kDa
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基因ID
- 57448
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NCBI登录号
- NP_057336
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UniProt
- Q9NR09
抗原
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