APOBEC3G 抗体 (N-Term)
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北京 101111
Quick Overview for APOBEC3G 抗体 (N-Term) (ABIN6990450)
抗原
See all APOBEC3G 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- APOBEC3G antibody will also detect the APOBEC3F isoform.
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纯化方法
- APOBEC3G Antibody is affinity chromatography purified via peptide column.
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免疫原
- APOBEC3G antibody was raised against a synthetic peptide corresponding to 15 amino acids near the amino-terminus of human APOBEC3G. The immunogen is located within the first 50 amino acids of APOBEC3G.
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亚型
- IgG
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anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (AA 60-330) antibody
APOBEC3G 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (AA 60-330) antibodyAPOBEC3G 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (C-Term) antibodyVerified APOBEC3G 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (AA 51-100) antibodyAPOBEC3G 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (N-Term) antibodyAPOBEC3G 适用: 人, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (AA 1-384) antibodyAPOBEC3G 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) antibodyAPOBEC3G 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (C-Term) antibodyAPOBEC3G 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (AA 191-384) antibodyAPOBEC3G 适用: 人, 大鼠, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) antibodyAPOBEC3G 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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APOBEC3G antibody can be used for detection of APOBEC3G by Western blot at 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 1 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- APOBEC3G Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- APOBEC3G antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- APOBEC3G (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G))
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别名
- APOBEC3G
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背景
- APOBEC3G Antibody: The Apoliprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5α, which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection as at least two isoforms, APOBEC3G and to a lesser extent APOBEC3F, can be incorporated HIV-1 virions and induce hypermutation in the newly synthesized viral DNA and thus destabilize the viral genome. This innate mechanism of retroviral resistance is counteracted by the HIV-1 Vif protein by inducing the ubiquitization and degradation of APOBEC3G, a single amino acid substitution (D128K) blocks APOBEC3G depletion without affecting its inhibitory activity.
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基因ID
- 60489
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NCBI登录号
- NP_068594
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UniProt
- Q9HC16
抗原
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