CARD14 抗体 (C-Term)
Quick Overview for CARD14 抗体 (C-Term) (ABIN6990437)
抗原
See all CARD14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- CARMA2 antibody is human specific. At least three isoforms of CARMA2 are known to exist, this antibody will only detect isoform 1. CARMA2 antibody is predicted not to cross-react with other CARMA proteins.
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纯化方法
- CARMA2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CARMA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human CARMA2. The immunogen is located within the last 50 amino acids of CARMA2.
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 249-523) antibody
CARD14 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 1-434) antibodyCARD14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (Center) antibodyCARD14 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 905-1004) antibodyCARD14 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4B3 unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 200-500) antibodyCARD14 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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CARMA2 antibody can be used for detection of CARMA2 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CARMA2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CARMA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
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别名
- CARMA2
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背景
- CARMA2 Antibody: CARMA proteins belong to the membrane-associated guan-ylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA2 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-κ,B activation. When expressed in cells, this protein activated NF-κ,B and induced the phosphorylation of BCL10 Alternative splicing of CARMA2 results in isoforms that possess differential effects on NF-κ,B activation and endoplasmic reticulum stress-induced cell death.
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基因ID
- 79092
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NCBI登录号
- NP_077015
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UniProt
- Q9BXL6
抗原
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