CARD11 抗体 (C-Term)
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- 抗原 See all CARD11 抗体
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- CARMA1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- CARMA1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1. The immunogen is located within the last 50 amino acids of CARMA1.
- 亚型
- IgG
- Top Product
- Discover our top product CARD11 Primary Antibody
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anti-Caspase Recruitment Domain Family, Member 11 (CARD11) antibody
CARD11 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) antibodyCARD11 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (Internal Region) antibodyCARD11 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (C-Term) antibodyVerified CARD11 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 481-580) antibodyCARD11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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CARMA1 antibody can be used for detection of CARMA1 by Western blot at 0.5 to 2 μ,g/mL. A band at approximately 125 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- CARMA1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- CARMA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- 别名
- CARMA1 (CARD11 产品)
- 别名
- BENTA antibody, BIMP3 antibody, CARMA1 antibody, PPBL antibody, 0610008L17Rik antibody, 2410011D02Rik antibody, CARD11 antibody, LOC100232755 antibody, caspase recruitment domain family member 11 antibody, caspase recruitment domain family, member 11 antibody, caspase recruitment domain-containing protein 11 antibody, CARD11 antibody, Card11 antibody, LOC100550812 antibody, card11 antibody
- 背景
- CARMA1 Antibody: CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the Iκ,K complex, thereby regulating activation of the NF-κ,B transcription factor. Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems.
- 基因ID
- 84433
- UniProt
- Q9BXL7
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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