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BCL2L14 抗体 (N-Term)

This anti-BCL2L14 antibody is a 兔 多克隆 antibody detecting BCL2L14 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990432
发货至: 中国

Quick Overview for BCL2L14 抗体 (N-Term) (ABIN6990432)

抗原

See all BCL2L14 抗体
BCL2L14 (BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14))

适用

人, 小鼠, 大鼠

宿主

  • 37
  • 2

克隆类型

  • 34
  • 5
多克隆

标记

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCL2L14 antibody is un-conjugated

应用范围

  • 30
  • 13
  • 13
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
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  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    Although antibody should react with both isoforms, only the Bcl-GS protein has been observed

    纯化方法

    Bcl-G Antibody is Ion exchange chromatography purified.

    免疫原

    Bcl-G antibody was raised against a peptide corresponding to 15 amino acids near the N-terminus of human Bcl-G. The immunogen is located within the first 50 amino acids of Bcl-G.

    亚型

    IgG
  • 应用备注

    Bcl-G antibody can be used for detection of Bcl-G by Western blot at 2.5 to 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Bcl-G Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Bcl-G antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BCL2L14 (BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14))

    别名

    Bcl-G

    背景

    Bcl-G Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.

    基因ID

    79370

    NCBI登录号

    NM_030766

    UniProt

    Q9BZR8
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