TP53INP1 抗体 (N-Term)
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北京 101111
Quick Overview for TP53INP1 抗体 (N-Term) (ABIN6990408)
抗原
See all TP53INP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- At least two isoforms of p53DINP1 are known to exist, this antibody will detect both isoforms.
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纯化方法
- p53DINP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- p53DINP1 antibody was raised with a synthetic peptide corresponding to 14 amino acids near the amino terminus of human p53DINP1. The immunogen is located within the first 50 amino acids of p53DINP1.
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亚型
- IgG
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anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 138-205) antibody
TP53INP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (Internal Region) antibodyTP53INP1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) antibodyKO Validated TP53INP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2710 unconjugated Recombinant Antibody
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 181-210), (C-Term) antibodyTP53INP1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29563 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 36-64), (N-Term) antibodyTP53INP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB29674 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (N-Term) antibodyTP53INP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibodyTP53INP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibodyTP53INP1 适用: 人, 猴 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 188-218), (C-Term) antibodyTP53INP1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 43-72), (N-Term) antibodyTP53INP1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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p53DINP1 antibody can be used for detection of p53DINP1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- p53DINP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- p53DINP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
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别名
- p53DINP1
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背景
- P53DINP1 Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-alpha and p53DINP1-beta or SIP27 and SIP18. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
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分子量
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Predicted: 18, 27 kDa
Observed: 30 kDa -
基因ID
- 94241
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UniProt
- Q96A56
抗原
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